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Ideally, a pharmacy POS should include HSA and FSA payment acceptance and should also integrate with your medical billing and pharmacy management systems.
Kymberlin earned her Bachelor of Arts in Creative Writing from Pacific University in 2020 and resides in Portland, Oregon.
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Kymberlin BushKymberlin earned her Bachelor of Arts in Creative Writing from Pacific University in 2020 and resides in Portland, Oregon.
Expert Contributor
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Matt has been helping small businesses make decisions since 2017. He has written reviews and articles across many different channels but specializes in the point of sale, payroll, and small business insurance categories and has been quoted in articles for Fox Business, Forbes, and other publications. Prior to joining Merchant Maverick, Matt was a journalist and editor for 14 years for a pair of weekly newspapers. He is a graduate of the University of Oregon and currently resides in Gladstone, Oregon.
REVIEWED BY
Matt ShermanMatt has been helping small businesses make decisions since 2017. He has written reviews and articles across many different channels but specializes in the point of sale, payroll, and small business insurance categories and has been quoted in articles for Fox Business, Forbes, and other publications. Prior to joining Merchant Maverick, Matt was a journalist and editor for 14 years for a pair of weekly newspapers. He is a graduate of the University of Oregon and currently resides in Gladstone, Oregon.
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Our content reflects the editorial opinions of our experts. While our site makes money through referral partnerships, we only partner with companies that meet our standards for quality, as outlined in our independent rating and scoring system.
The best POS systems for pharmacies will also include specific features like HSA/FSA payment acceptance, medical billing and pharmacy management system integrations, and even online ordering or prescription delivery.
Features like multi-store support, customer loyalty programs, reporting, and inventory/delivery management make some POS systems stand out as great choices for pharmacies. Our top picks include:
For single/multi-location retail businesses looking for a strong loyalty program and advanced business reporting
Lightspeed also has quote-based enterprise pricing for large businesses.
All plans come with one POS register. Extra registers can be added for an additional monthly fee.
Lightspeed Retail Features
Lightspeed Retail Features
Availability
Multi-Store Support
Contactless Payments
Multi-Channel Selling
Core plan and up
Gift Cards
Customer Loyalty
Core plan and up
Marketing Tools
Core plan and up
Online Ordering
Inventory Management
Reporting
Menu Management
Delivery Management
EBT Acceptance
Employee Management
Text Messaging
Lightspeed is one of the best retail POS systems. It is especially well-suited for retail establishments processing large amounts of transactions every day, like a pharmacy.
This is because Lightspeed is the leader as one of the best POS systems for inventory management. This pharmacy POS harnesses the power of the cloud to provide advanced retail features, including inventory management, vendor management, customer management, loyalty, accounting, and eCommerce.
Lightspeed is as flexible as it is powerful; its open API allows you to build your own third-party pharmacy software integrations to customize your perfect pharmacy POS.
Lightspeed Retail Hardware
Lightspeed’s POS hardware is iPad-based, and you’ll have to contact the company for a personalized quote. You can also source your hardware yourself.
Note: Lightspeed Retail now requires all new and existing qualified merchants using Lightspeed Retail in the US and Canada to sign up for Lightspeed Payments, Lightspeed’s payment processor. If you currently use a card reader from a third-party payment processor, you can’t use it anymore. Since you can’t use any existing payment terminals (card readers) with Lightspeed Payments, Lightspeed is currently running a free terminal replacement promotion for eligible merchants that includes two free Lightspeed POS terminals (card readers) per qualified merchant.
Eligible merchants include business owners that process a minimum of $100/day in credit card payments, as measured by a monthly average. Apple products are not included in this promotion, so you’ll still need to source an iPad to take sales.
Lightspeed Retail Payment Processing
Lightspeed provides flat-rate payment processing via Lightspeed Payments at a rate of 2.6% + $0.10.
Note: Lightspeed will buy out payment processing contracts, paying off merchants’ early cancellation fees if you process a minimum of $25,000 in card sales and then submit documentation of your previous payment processing contract that states your early termination fee within six months of meeting this minimum processing amount.
It’s important to note that the “paying off” comes in the form of discounted payment processing fees, not a chunk of cash that goes towards your termination fees when you decide to switch to Lightspeed Payments.
If you are a current Lightspeed user and don’t apply for Lightspeed Payments within 30 days of receiving a notification email, you’ll be charged a fee between $200 and $1,120 per month until you do sign up for Lightspeed Payments.
What To Watch Out For
To get the best pricing for Lightspeed, you’ll need to prepay for one year. However, we often advise readers to sign up for short-term monthly plans before dedicating themselves to the long term. This is because many POS providers (Lightspeed included) charge an early termination fee for canceling a plan early.
You also need to use Lightspeed Payments to get the best monthly subscription rate. If you use a different integrated payment processor, you will pay an extra monthly fee to do so. This extra fee may be worth it for larger businesses that can offer better payment processing rates than Lightspeed.
If you purchase hardware from Lightspeed, you must confirm that you have received it within five business days. Otherwise, your hardware will not be covered under Lightspeed’s hardware warranty (14 days for Apple products and 30 days for non-Apple products).
Lightspeed Retail Is Best For Pharmacies That:
Need advanced retail reporting, inventory tracking, and employee management
If your high-volume or large business needs an enterprise-level solution
Unlimited devices are supported on all plans. To add the full suite of POS features, including advanced inventory, you’ll need to add Shopify Pro, which is an additional monthly fee.
Shopify also offers a Shopify Starter plan for mobile processing only and Shopify Plus plans for enterprise-level businesses.
Shopify Features
Shopify POS Features
Availability
Multi-Store Support
Supports multiple inventory locations
Contactless Payments
Multi-Channel Selling
Gift Cards
Customer Loyalty
Marketing Tools
Online Ordering
Inventory Management
Reporting
Menu Management
Delivery Management
EBT Acceptance
Employee Management
Text Messaging
Shopify is a complete commerce solution for both online and brick-and-mortar businesses. However, Shopify especially shines in terms of its eCommerce features. If you work with a developer, there’s nothing you can’t do with a Shopify website. Notably, Shopify Plus powers multiple enterprise-level online pharmacies, including Meagher’s Pharmacy and Lloyd’s Pharmacy.
Even for a smaller pharmacy, Shopify has numerous eComm integrations that can be useful for pharmacies that want to sell in-person and online, including SnapRx, Retail Management Solutions, and various age verification apps.
Shopify Hardware
Shopify sells hardware bundles and individual hardware components; you can also source your iPad or Android POS hardware yourself. Shopify’s most affordable bundle includes a stand for a 9.7″ iPad and a card reader.
Shopify Payment Processing
Shopify has an in-house payment processing service called Shopify Payments, which is powered by Stripe. Rates are 2.4 – 2.9% and are based on which Shopify plan you’re on.
You can also integrate a payment processor of your choice for an additional transaction fee.
What To Watch Out For
All Shopify plans are month-to-month with no long-term commitment required. Note that Shopify Payments is a payment service provider similar to Square or PayPal, which means you will not have your own dedicated merchant account.
Get a free card swiper from Square at no cost when you create a free account. Claim your card reader.
Pros
Accepts FSA/HSA cards
Integrates with EHR and medical billing software
Free POS app & website
Cons
Must use Square for payment processing
Why We Chose Square As The Most Budget-Friendly Pharmacy POS
Need a low-risk, low-commitment, low-cost POS system? Square is the first place you should probably look no matter what kind of business you own.
We love the robust features available to pharmacies at little to no cost including FSA/HSA acceptance, EHR and medical billing software integrations, and Square's great free POS app and website.
Square POS has no monthly fee. Square also offers two versions of Square for Retail if you want advanced inventory features, including a free and paid version.
Square Features
Square POS Features
Availability
Multi-Store Support
Contactless Payments
Multi-Channel Selling
Gift Cards
Add-on
Customer Loyalty
Add-on
Marketing Tools
Online Ordering
Inventory Management
Reporting
Menu Management
With Square for Restaurants
Delivery Management
Add on
EBT Acceptance
Employee Management
Text Messaging
For a free POS app, Square offers a ton of functionality.
Not only is Square perfect for basic, easy-to-use payment processing, but this free POS also has a ton of extensions and app integrations that extend its functionality for any business type, including healthcare businesses such as pharmacies. Some examples include DrChrono EHR & RCM, Remedly, IntakeQ, and Reference Health Payments.
Square also includes FSA and HSA payment acceptance out-of-the-box as long as you have an eligible MCC (merchant category code). Even enterprise-level companies such as QuigMeds have integrated Square technology into their pharmacy POS systems.
Square Hardware
Square sells POS hardware for iPad as well as its proprietary Square Register and Square Terminal; you can also source your POS hardware yourself.
Square accounts come with a free card swiper, though most pharmacies will want a more secure chip and tap reader, which you can use with an iPad or Android tablet.
Square Payment Processing
Square charges a flat rate of 2.6% + $0.10 for all in-person transactions. Square also offers custom pricing for enterprise businesses that process over $250K/month.
You do not have the option to use a different payment processor with Square.
What To Watch Out For
All Square plans are month-to-month with no long-term commitment required. Square is a third-party payment processor/payment service provider rather than a merchant account provider, which can result in account stability problems for certain businesses.
Square Is Best For Pharmacies That...
Want an affordable or free and comprehensive POS system
Why We Chose Cashier Live For The Best Pharmacy Software Integrations
Cashier Live offers something the other POS systems on this list don't: a dedicated pharmacy plan.
Its dedication to this industry allows the company to offer important pharmacy software integrations like SpeedScript, HBS, Carepoint, RNA, and MethCheck (for pseudoephedrine sales).
Cashier Live Pricing
Cashier Live’s pharmacy plan pricing is quote-based. However, the company says its software provides the best value in the industry, with no hidden fees.
Though Cashier Live doesn’t list its pharmacy plan pricing, the company’s standard retail package is $75/month, which is quite reasonable.
Cashier Live Features
The main benefit of using Cashier Live is that it has pharmacy POS features out of the box, including built-in integrations with other pharmacy software systems. In fact, Cashier Live was the first web-based SIGIS (Special Interest Group for IIAS Standards)-compliant POS system built for pharmacy needs.
Other pharmacy-specific POS systems tend to be locally-installed and exorbitantly expensive, so Cashier Live is a great cloud-based alternative. Some industry-specific integrations included with Cashier Live are SpeedScript, HBS, Carepoint, RNA, and MethCheck (for pseudoephedrine sales).
Cashier Live Hardware
Cashier Live can run on iOS, Android, or a computer, which gives you the option to source hardware components yourself. However, the company’s hardware bundles are on the expensive side.
Cashier Live Payment Processing
Cashier Live offers a flat rate of 2.7% on each transaction. The POS company does not integrate with other processors.
What To Watch Out For
Cashier Live contracts are billed month-to-month with no long-term contract required. However, you can receive a discount if you commit to a year or more.
Cashier Live Is Best For Pharmacies That...
Have important existing pharmacy software integrations
Need a pharmacy management integration
Want prescription wholesaler purchase ordering features
Proprietary hardware can’t be used with other systems
Sold by some low-quality resellers
Why We Think Clover Is The Easiest To Use
Clover is hand-down one of the best plug-and-play POS systems on the market.
Pharmacies looking for a POS system that is quick to learn, train, and troubleshoot could do much worse than Clover. While it isn't a pharmacy-specific POS, there are plenty of third-party integrations you can use to make Clover a great POS for you.
Clover offers a variety of plans, including a plan just for payment processing up to plans for full-service restaurants.
Clover Features
Clover POS Features
Availability
Multi-Store Support
Contactless Payments
Depends on hardware choice
Multi-Channel Selling
Gift Cards
Customer Loyalty
Marketing Tools
Online Ordering
Based on software plan
Inventory Management
Reporting
Menu Management
Delivery Management
EBT Acceptance
Add-on app
Employee Management
Text Messaging
Clover is an incredibly easy-to-use system that’s a breeze to set up and train your employees on. Pretty much as soon as you receive your POS hardware, you can plug it in, activate it, and start taking payments.
It’s a good system for basic payment acceptance if you don’t need a lot of pharmacy-specific features — although its REST API means you can integrate other REST-ful applications. Clover is not IIAS-compliant (which is required to accept HSA/FSA payments as a non-medical retailer), but as long as you have an eligible MCC code (MCC 5912 or 5122 for pharmacies), you can accept HSA and FSA cards with Clover.
Clover Hardware
Clover’s hardware includes its flagship Clover Station POS. If you want a customer-facing screen, you can upgrade to the Clover Station Duo. Other hardware options include the Clover Mini and the mobile Clover Flex.
Clover Payment Processing
If you purchase your system directly from Clover, payment processing fees start at 2.3% – 2.6% + $0.10% per transaction, depending on your monthly software plan.
Various other entities also sell Clover with different (and often more expensive) payment processing structures.
What To Watch Out For
Hundreds of different merchant service providers sell Clover, and not all of them are top-notch. While software purchased from Clover directly is all month-to-month with the ability to cancel at any time, other providers may sell Clover with sneaky long-term contracts and hidden fees.
Clover Is Best For Pharmacies That...
Need a plug-and-play POS system
Want to choose a healthcare-friendly payment processor
Merchant Maverick has been researching and reviewing POS providers since 2012. Our writers have tested over 100 different point of sale systems, evaluating pricing, features, ease of use, customer service, and user reviewers. Read more about how we rate POS providers.
Weighted Rating Breakdown
Pricing 40%
Features 30%
Ease Of Use 15%
Customer Service 10%
User Reviews 5%
When comparing different POS software systems, we consider many data points, including relative pricing, the depth of niche features offered, the price of hardware, and any associated payment processing fees. Our lists of the best providers include only apps we’ve deemed worthwhile from multiple vantage points. The POS vendors we pick share qualities such as widespread availability, accessibility, user-friendliness, and reasonable pricing. We also look carefully at niche features, such as check-splitting, inventory management, eCommerce, loyalty programs, gift cards, and more.
We spend an average of 10-15 hours researching and updating each one of our lists, making sure the providers included meet our internal standards for quality and reputation.
80+
Vendors evaluated
65+
Attributes assessed per vendor
20+
Features weighed
30+
Combined years of experience
Finding The Best Pharmacy Point Of Sale System
When it comes to choosing among the above pharmacy pos systems it’s important to verify that the POS does everything you need it to. This is especially necessary for a highly regulated industry such as the pharmacy industry.
For example, you may need an IIAS-compliant system to accept FSA or HSA cards (the IRS requires this if less than 90% of your gross sales are from prescriptions and over-the-counter qualifying healthcare products). Or, if you run an online-only pharmacy that fulfills prescriptions based on telephone consults, you’ll likely need a high-risk merchant account.
Additionally, you will need to determine if a POS can integrate with your insurance billing and pharmacy management systems.
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The vendors that appear on this list were chosen by subject matter experts on the basis of product quality, wide usage and availability, and positive reputation.
Merchant Maverick’s ratings are editorial in nature, and are not aggregated from user reviews. Each staff reviewer at Merchant Maverick is a subject matter expert with experience researching, testing, and evaluating small business software and services. The rating of this company or service is based on the author’s expert opinion and analysis of the product, and assessed and seconded by another subject matter expert on staff before publication. Merchant Maverick’s ratings are not influenced by affiliate partnerships.
Our unbiased reviews and content are supported in part by affiliate partnerships, and we adhere to strict guidelines to preserve editorial integrity. The editorial content on this page is not provided by any of the companies mentioned and has not been reviewed, approved or otherwise endorsed by any of these entities. Opinions expressed here are author’s alone.
We Recommend Square POS For Your Business 🏆User-friendly & feature-rich point of sale system with affordable pricing.Square POS is an intuitive and simple point of sale platform. It offers customizable tools and a variety of add-ons to fit your business needs and reach your goals.Get StartedNo credit card required